Štavalj (Rumex crispus L.-Polygonaceae)
Štavalj (Rumex crispus L.- Polygonaceae)
CURLED DOCK FOR HOMOEOPATHIC PREPARATIONS RUMEX CRISPUS FOR HOMOEOPATHIC PREPARATIONS Rumex crispus ad praeparationes homoeopathicas DEFINITION Fresh root of Rumex crispus L. CHARACTERS Macroscopic characters described under identification. Pungent smell. IDENTIFICATION Taproot, fleshy, saffron yellow with a surface furrowed with wrinkles and annular striations. TESTS Foreign matter (2.8.2): maximum 5 per cent. Loss on drying (2.2.32): minimum 50.0 per cent, determined on 5.0 g of finely-cut drug by drying in an oven at 105 °C for 2 h. STOCK DEFINITION Curled dock mother tincture complies with the requirements of the general technique for the preparation of mother tinctures (see Homoeopathic Preparations (1038) and French Pharmacopoeia Authority Supplement). The mother tincture is prepared with ethanol (45 per cent V/V), using the fresh root of Rumex crispus L. Content: minimum 0.003 per cent m/m of total hydroxyanthracene derivatives, expressed as emodin (C15H10O5; Mr 270.2).
CHARACTERS Appearance: reddish-brown liquid. IDENTIFICATION Thin-layer chromatography (2.2.27). Test solution. Mother tincture. Reference solution. Dissolve 10 mg of emodin R and 5 mg of dihydroxyanthraquinone R in 20 mL of methanol R. Plate: TLC silica gel plate R.
TESTS Ethanol (2.9.10): 40 per cent V/V to 50 per cent V/V. Dry residue (2.8.16): minimum 1.2 per cent m/m. ASSAY Ultraviolet and visible absorption spectrophotometry (2.2.25).
Calculate the percentage content m/m of total hydroxyanthracene derivatives, expressed as emodin, from the expression: 12 21 m×A p×1.25×m×A A1 = absorbance of the test solution, A2 = absorbance of the reference solution, m1 = mass of the mother tincture sample, in grams, m2 = mass of emodin sample in the reference solution, in grams, p = percentage content of emodin in emodin R.
French Pharmacopoeia 2007