Preparati

FERTILITET PLUS 6 MIX Kompozitna formula kod smanjenog fertiliteta                                                                            

FERTILITET PLUS 6 MIX (Formula composita ad Sterilitas feminae ICD-10 N97)

MEŠAVINA 6 MATIČNIH TINKTURA – hidroetanolni tečni ekstrakti svežih delova biljaka

MKB-10: N97 smanjen fertilitet žene (Sterilitas feminae ICD-10 N97)

ICD-10: N97 Female infertility

U skladu sa:

Eu. Ph. 8,  01.07.2015. monografijama, status june 2015.:

Marrubium vulgare (Lamiaceae), herba: 07/09/2007, Marrubii herba 1835;

Achilea millefolium (Asteraceae), 10/01/2008, Millefolii herba, 1382;

Alchemilla vulgaris (Rosaceae), herba, 01/07/2015, Alchemillae herba,1387;

Geranium robertianum (Geraniaceae), herba, Geranii robertiani herba;

Trifolium pratense (Fabaceae), flos, Trifolium pratense hom., HPUS78;

Urtica dioica (Urticaceae), folium, 23/11/2005, Urticae folium, 1897; Urticae radix, 2538.

a) Based on Article 10a of Directive 2001/83/EC as amended (well-established use), Based on Article 16d(1), Article 16f and Article 16h of Directive 2001/83/EC as amended (traditional use),

DIRECTIVE 2004/24/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 31 March 2004.

b). EMA/HMPC/, Committee on Herbal Medicinal Products (HMPC): Assessment report on Marrubium vulgare, herba; Achilea millefolium, herba; Alchemila vulgaris, herba; Geranium robertianum, herba; Trifolium pratense, flos; Urtica dioica, folium.

v) EMA/HMPC/, Committee on Herbal Medicinal Products (HMPC): Community herbal monograph onAssessment report onMarrubium vulgare, herba; Achilea millefolium, herba; Alchemila vulgaris, herba; Geranium robertianum, herba; Trifolium pratense, flos; Urtica dioica, folium.

g) Fr. Ph. ANSM (Pharmacopée française:Marrubium vulgare; Achilea millefolium; Alchemila vulgaris; Geranium robertianum; Trifolium pratense; Urtica dioica ad praeparationes homoeopathicas.

Biljni preparat u tečnom obliku (nerazblaženi ili razblaženi) za oralnu upotrebu.

a) flos( fresh flower),

b) fructus (fresh fruit),

c) herba (fresh whole flowering plant).

Sastav:

mešavina matičnih tinktura:

a) tečni ekstrakt (DER 1:1), ekstrakcioni rastvarač etanol 51% (v/v),

b) tečni ekstrakt (DER 1:2), ekstrakcioni rastvarač etanol 65% (v/v),

c) tečni ekstrakt (DER 1:5), ekstrakcioni rastvarač etanol 70% (v/v),

u sledećem odnosu:

FERTILITET PLUS 6 MIX, sadrži preko 1000 hemijskih jedinjenja koja ispoljavaju preko 1400 istraženih dejstava *(podaci ažurirani septembra 2016. -pogledati za svaku matičnu tinkturu posebno od gore navedenih preparata).

Sadržaj:

a) minimalno (za svaku matičnu tinkturu posebno od gore navedenih preparata),

b) u većoj koncentraciji sadrži (pogledati za svaku matičnu tinkturu posebno od gore navedenih preparata),

v) više od svih biljaka sadrži (pogledati za svaku matičnu tinkturu posebno od gore navedenih preparata).

Indikacije:

Biljni preparati su namenjeni poboljšanju opšteg stanja organizma kroz razna naučno dokazana dejstva.

Upotreba kod smanjenog fertiliteta i tegoba genitalnog trakta.

Dr. Džems Djuk (Dr. James Duke) u Handbook of Medicinal Herbs, 2nd Ed. (2002). CRC Press, navodi sledeće:

 – ima jako dejstvo kod: tegoba urogenitalnog trakta i pada fertiliteta

 – delotvoran kod:

– upotrebljava se kao: jak Ca preventiv, antispazmodik, antiinflamatik,  antibakterik, antioksidant, (podaci Dr. James A. Duke).

Marrubium vulgare: antibacterial, Cancer-preventive, antiinflammatory, antiviral, antioxidant, antimutagenic,

aldose-reductase-inhibitor, antitumor, apoptotic, antiHIV, antispasmodic, antiseptic, hepatoprotective, antiherpetic,

insectifuge, antiulcer, antifeedant, choleretic, antihistaminic, antitumor (Lung), hypocholesterolemic, antitumor-promoter, ornithine-decarboxylase-Inhibitor, analgesic, antihepatotoxic, anticancer,

Achilea millefolium: antibacterial, antiinflammatory, antioxidant,  insectifuge, antispasmodic, antiseptic, Cancer-preventive, flavor, perfumery,  fungicide, antiviral, analgesic, antitumor, sedative, antimutagenic, antiulcer, aldose-Reductase-Inhibitor, antiherpetic, nematicide, hepatoprotective, antifeedant, antiradicular, hypocholesterolemic, diuretic, candidicide, antiallergic, vasodilator, expectorant, antihepatotoxic, antidiabetic, immunostimulant, choleretic, antiasthmatic, antiacne, insecticide, antihistaminic,

Alchemilla vulgaris: Alchemilla vulgaris, Bundesanzeiger Nr. 22 a vom 3.2.1988 Monographie BGA/BfArM (Kommission D); Lady’s Mantle (Alchemillae herba), Published September 18, 1986. List of German Commission E Monographs (Phytotherapy)

Geranium robertianum: Cancer, astringent, Cancer(Prostate), diabetes, diarrhea, diuretic, gargle, hematochezia, hemostat, plague, sore, sore(throat), throat, tonic, Tumor

Trifolium pretense: allergenic, hypocholesterolemic, aldose-reductase-Inhibitor, Insectifuge, antiulcer, antidiabetic, antiradicular, diuretic, estrogenic, sedative, antiarthritic, hepatoprotective, nematicide, vasodilator, perfumery, antiosteoporotic, cardioprotective, immunostimulant, hypoglycemic, antifeedant, antihistaminic, anticataract, irritant, immunomodulator, antiaggregant, anticancer

Urtica dioica: Cancer-preventive, antioxidant, antibacterial, antitumor, antiinflammatory, antimutagenic, hepatoprotective, antiviral, antiseptic, fungicide, hypotensive, hypocholesterolemic, antiradicular, antiulcer, antidiabetic, antispasmodic, antihepatotoxic, diuretic, aldose-reductase-Inhibitor, antiarthritic, choleretic, analgesic, allergenic, flavor, hypoglycemic, vasodilator, antitumor-promoter, antiherpetic, antiatherosclerotic, immunomodulator, cardioprotective, anticancer, immunostimulant, antileukemic, antiaggregant, antidepressant, antihistaminic, antiHIV, anticataract,

Doziranje i način primene:

do 2 mL (80 kapi) podeljeno u 2 do 4 doze.

Biljni preparat FERTILITET PLUS 6 MIX:

pojedinačna doza: 0,5-1 mL, preporučena dnevna doza (PDD): 2 mL.

Oralna primena, 15 minuta pre obroka.

Napraviti pauzu posle 4 nedelje neprekidne upotrebe preparata.

Po preporukama, preparat postiže najbolje efekte pri upotrebi od 8 do 12 nedelja, duža upotreba je bezbedna uz pauze.

Kontraindikacije:

preosetljivost na aktivne supstance,

preosetljivost na biljke porodice *(pogledati za svaku matičnu tinkturu posebno od gore navedenih).

Čuvanje:

na tamnom, suvom i hladnom mestu do 20˚C, van domašaja dece i izlaganja EM zračenju, u dobro zatvorenoj originalnoj ambalaži.

Rok upotrebe:

5 godina, posle prvog otvaranja 6 meseci. Ako se čuva po preporučenim uslovima, rok trajanja je neograničen.

Pakovanje:

50 mL i 100 mL, standardne farmaceutske braon bočice; 250 mL, 500 mL, 1000 mL i 5000 mL na zahtev.

Nutritivne informacije:

FERTILITET PLUS 6 MIX:

energetska vrednost u 100 mL: 1504 kJ/ 360 kcal,

u preporučenoj dnevnoj dozi (PDD) 2 mL: 30kJ/ 7,17 kcal,

suve materije (DR) više od 1,9% (Fr. Ph.), 1,4% RD 0,935 – 0,955 (HAB2010).

Bez konzervanasa, proteina, masti i ugljenih hidrata.

FERTILITET PLUS 6 MIX je rukom rađen proizvod. 

Navedene matične tinkture ulaze u sastav preparata RESPIRO 30 za kog je obavljena analiza na teške metale, pesticide i mikrobiološku ispravnost broj 4603120601 od 29.03.2016. godine . Analizu izvršila ANAHEM LABORATORIJA BEOGRAD.

CENOVNIK

FERTILITET PLUS 6 MIX, MEŠAVINA MATIČNIH TINKTURA,

50 mL – 750,00 RSD (6,25€);   100 mL – 1500,00 RSD (12,5€).

Pogledati ostale podatke na:

http://www.biljni-preparati.com/preparati/fertilitet-6-mix-formula-composita-ad-sterilitas-feminae-icd-10-n97/

Podaci ažurirani decembra 2017.

Marrubium vulgare: antibacterial, Cancer-preventive, antiinflammatory, antiviral, antioxidant, antimutagenic, aldose-reductase-inhibitor, antitumor, apoptotic, antiHIV, antispasmodic, antiseptic, hepatoprotective, antiherpetic, insectifuge, antiulcer, antifeedant, choleretic, antihistaminic, antitumor (Lung), hypocholesterolemic, antitumor-promoter, ornithine-decarboxylase-Inhibitor, analgesic, antihepatotoxic, anticancer

Reference:

Planta Medica, 57: A43, 1991.

Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.

Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.

Martindale’s 28th

Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.

Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.

Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.

Achilea millefolium:

antibacterial, antiinflammatory, antioxidant,  insectifuge, antispasmodic, antiseptic, Cancer-preventive, flavor, perfumery,  fungicide, antiviral, analgesic, antitumor, sedative, antimutagenic, antiulcer, aldose-Reductase-Inhibitor, antiherpetic, nematicide, hepatoprotective, antifeedant, antiradicular, hypocholesterolemic, diuretic, candidicide, antiallergic, vasodilator, expectorant, antihepatotoxic, antidiabetic, immunostimulant, choleretic, antiasthmatic, antiacne, insecticide, antihistaminic,

Reference:

Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.

HerbalGram No. 22 – Spring 1990, page 14.

Aloe Research Council – Duke writeup of non-peer reviewd book by Coats and draft by Henry

Merck 11th Edition

Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.

Merck 11th Edition

Economic & Medicinal Plant Research, 6: 235.

Al-Khalil, S. 1996. Inhibition of Lens Alkaloids Reductase by Protopine Alkaloids. Saudi Pharm J, 4(1): 45-47.

Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.

Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.

Angewandte Botanik 68(5/6)=1994. Page 195.

Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.

Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.

Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).

Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

Geranium robertianum:

Cancer, astringent, Cancer(Prostate), diabetes, diarrhea, diuretic, gargle, hematochezia, hemostat, plague, sore, sore(throat), throat, tonic, Tumor

Reference:

Uphof, J.C. Th. 1968. Dictionary of economic plants. 2nd ed. Verlag von J. Cramer.

Steinmetz, E.F. 1957. codex Vegetabilis. Published by the author, Amsterdam.

Font Query, P. 1979. Plantas Medicinales el Dioscorides Renovado. Editorial Labor, S.A. Barcelona. 5th Ed.

Hartwell, J.L. 1967-71. Plants used against cancer. A survey. Lloydia 30-34.

Trifolium pretense:

allergenic, hypocholesterolemic, aldose-reductase-Inhibitor, Insectifuge, antiulcer, antidiabetic, antiradicular, diuretic, estrogenic, sedative, antiarthritic, hepatoprotective, nematicide, vasodilator, perfumery, antiosteoporotic, cardioprotective, immunostimulant, hypoglycemic, antifeedant, antihistaminic, anticataract, irritant, immunomodulator, antiaggregant, anticancer

Reference:

Aloe Research Council – Duke writeup of non-peer reviewd book by Coats and draft by Henry

Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.

Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.

Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.

Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.

Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X – The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95

Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.

Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.

Journal of Medicinal Food 2: 163.1999.

Shoyakugaku Zasshi, 44: 183.

Medline (post 1990 searches filed in my computer

Urtica dioica:

Cancer-preventive, antioxidant, antibacterial, antitumor, antiinflammatory, antimutagenic, hepatoprotective, antiviral, antiseptic, fungicide, hypotensive, hypocholesterolemic, antiradicular, antiulcer, antidiabetic, antispasmodic, antihepatotoxic, diuretic, aldose-reductase-Inhibitor, antiarthritic, choleretic, analgesic, allergenic, flavor, hypoglycemic, vasodilator, antitumor-promoter, antiherpetic, antiatherosclerotic, immunomodulator, cardioprotective, anticancer, immunostimulant, antileukemic, antiaggregant, antidepressant, antihistaminic, antiHIV, anticataract,

Reference:

Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

Economic & Medicinal Plant Research, 5: 194.

Economic & Medicinal Plant Research, 6: 235.

Economic & Medicinal Plant Research, 6: 165

Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X – The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95

Martindale’s 30th

Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.

List, P.H. and Horhammer, L., Hager’s Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.

Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387

Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill.

Aloe Research Council – Duke writeup of non-peer reviewd book by Coats and draft by Henry

Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.

Life Sciences 55: 1061.

Martindale’s 29th