Dren (Cornus mas L.)
BILJNI PREPARATI DRENA:
TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN HSS, DER 1:5 i
MATIČNA TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN TM, DER 1:2
Tinctura Corni Fructus DER 1:5,
Corni fructus recentis extractum ethanolicum liquidum DER 1:2
BILJNI PREPARATI DRENA:
TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN HSS, DER 1:5 i
MATIČNA TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN TM, DER 1:2
Tinctura Corni Fructus DER 1:5,
Corni fructus recentis extractum ethanolicum liquidum DER 1:2
ATC: – antidijaroik, antidizenterik, antipiretik, adstrigent, ekspektorant, stomahik,
U skladu sa:
Eu. Ph. monografijom:
EMEA: Assessment report on Cornus mas L., fructus
Fr. Ph. ANSM Cornus mas ad praeparationes homoeopathicas
Biljni preparat u tečnom obliku (nerazblažen ili razblažen) za oralnu i lokalnu upotrebu.
a) Cornus mas L., fructus (Dogwood fresh fruit).
Sastav: a) tečni ekstrat (DER 1:2), ekstrakcioni rastvarač etanol 65% (v/v).
Cornus mas L., sadrži 22 istražena hemijska jedinjenja koja ispoljavaju 296 dejstava ( podaci ažurirani juna 2019.)
Sadržaj:
a) minimalno 0,01% m/m, iridoida (iridoids), izraženih kao loganska kiselina (loganic acid) (MF: C16H24O10MW: 376,355760 g/mol−1),
b) u većoj koncentraciji sadrži linolnu kiselinu (linoleic acid) najviše posle Silybum marianum, oleic acid, gallic acid, palmitic acid, ellagic acid, moronoside, hexahydroxydiphenic acid, ursolic acid, secologanin, stearic acid, rutin quercetin,
c) najviše od svih biljaka sadrži iridoida.
Indikacije: biljni preparati su namenjeni poboljšanju opšteg stanja organizma kroz razna naučno dokazana dejstva.
Upotreba kod gastrointestinalnih tegoba.+
– ima jako dejstvo kod: dijareje i dizenterije, …
– delotvoran kod: konstipacije, grčeva, malarije, gihta, visoke temperature, hemoroida, …
– u narodnoj medicini kod: malarične groznice, antraksa, anoreksije, bola u leđima, Ca. dojke, prehlade, grčeva, dijareje, dizenterije, dispepsije, erizipela, groznice, gripa, glavobolje, hepatitisa, promuklosti, hiperaciditeta, histerije, žutice, indolentnog ulcera, leukemije, mastitisa, boginja, mialgije, neurastenije, pneumonije, stomatitisa, tifusa, ulceracija, infekcije crvima i crevnim parazitima, …
– spoljašnja primena kod: povreda, ekcema, infekcija kože, …
– upotrebljava se kao: antispazmodik, biter, kardioaktiv, laksativ, moluscicid, … antioksidans, analgetik, antidot, antipiretik, antiseptik, aperient, aperitiv, adstringent, antimalarik, baktericid, depurativ, digestiv, stimulant, stomahik, tonik, …
Doziranje i način primene:
do 2 mL (80 kapi) podeljeno u 2 do 4 doze.
Biljni preparat DREN HSS i TM:
pojedinačna doza: 0,5-1 mL,
preporučena dnevna doza (PDD): 2 mL.
Oralna (sat vremena pre obroka) i lokalna primena.
Upotreba na koži: aplicirati na obolelo mesto u tankom sloju ili obliku impregniranog zavoja.
Napraviti pauzu posle 4 nedelje neprekidne upotrebe.
Po preporukama, preparat postiže najbolje efekte pri upotrebi od 8 do 12 nedelja, duža upotreba je bezbedna uz pauze.
Kontraindikacije: preosetljivost na aktivne supstance, preosetljivost na biljke porodice (genus Cornus, family Cornaceae).
Čuvanje: na tamnom, suvom i hladnom mestu do 20˚C, van domašaja dece i izlaganja EM zračenju, u dobro zatvorenoj originalnoj ambalaži.
Rok upotrebe: 5 godina, posle prvog otvaranja 6 meseci.
Pakovanje: 50 mL i 100 mL, standardne farmaceutske braon bočice; 250 mL, 500 mL, 1L i 5 L na zahtev.
Nutritivne informacije:
DREN HSS i TM:
energetska vrednost u 100 mL: 1504 kJ/ 360 kcal,
u preporučenoj dnevnoj dozi (PDD) 2 mL: 30 kJ/ 7,17 kcal,
suve materije (DR) više od 2,5% (Fr. Ph.).
Bez konzervanasa, proteina, masti i ugljenih hidrata.
DREN HSS i TM su rukom rađeni proizvodi.
TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN HSS, DER 1:5
RSD 500,00/ 50 mL, RSD 1000,00/ 100 mL, i
MATIČNA TINKTURA – hidroetanolni tečni ekstrakt svežeg ploda, DREN TM, DER 1:2,
RSD 600,00/ 50 mL, RSD 1200,00/ 100 mL
Activity (spisak dejstava po broju bioaktivnih jedinjenja)
Antiinflammatory
Cancer-Preventive
Pesticide
Antibacterial
Antiviral
Hepatoprotective
Antimutagenic
Antitumor
Antioxidant
Antiperoxidant
AntiHIV
Cytotoxic
Apoptotic
Antitumor-Promoter
Antihistaminic
Immunomodulator
Antiherpetic
Anticancer
Antiulcer
Antiradicular …
Common names: Cornelian Cherry; Sorbet How used Medicinal
Activities: 296 Chemicals w/Activities: 16 All Chemicals: 22
Chemical
*Reference
LINOLEIC-ACID
Kleiman, R., Spencer, G. F. 1982. Search for New Industrial Oils: 16. Umbelliflorae-Seed Oils Rich in Petroselinic Acid. J. Amer. Oil Chem. Soc., 59: 29-32.
OLEIC-ACID
Kleiman, R., Spencer, G. F. 1982. Search for New Industrial Oils: 16. Umbelliflorae-Seed Oils Rich in Petroselinic Acid. J. Amer. Oil Chem. Soc., 59: 29-32.
URSOLIC-ACID
Grigorescu, E., Ionescu, A. P. 1976. Isolation of Ursolic Acid from Cornus mas (Cornaceae). Phytochemistry, 15: 1097.
GALLIC-ACID
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
STEARIC-ACID
Hohn, M. E., Meinschein, W. G. 1976. Seed Oil Fatty Acids: Evolutionary Significance in the Nyssaceae and Cornaceae. Biochem. Syst. Ecol., 4: 193-199.
GALLIC-ACID
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
RUTIN
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
ELLAGIC-ACID
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
RUTIN
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
ELLAGIC-ACID
Delaveau, P., Paris, R. R. 1961. Concerning the Presence of Rutoside and Gallic Derivatives from the Flowers of Cornus mas and Preliminary Research with C. sanguinea. Bull Soc Chim Biol, 43: 661-666.
QUERCETIN
Bate-Smith, E. C., Ferguson, I. K., Hutson, K., Jensen, S. R., Nielsen, B. J., Swain, T. 1975. Phytochemical Interrelationships in the Cornaceae. Biochem. Syst. Ecol., 3: 79.
PROCYANIDIN
Bate-Smith, E. C., Ferguson, I. K., Hutson, K., Jensen, S. R., Nielsen, B. J., Swain, T. 1975. Phytochemical Interrelationships in the Cornaceae. Biochem. Syst. Ecol., 3: 79.
OLEIC-ACID
Hohn, M. E., Meinschein, W. G. 1976. Seed Oil Fatty Acids: Evolutionary Significance in the Nyssaceae and Cornaceae. Biochem. Syst. Ecol., 4: 193-199.
LINOLEIC-ACID
Hohn, M. E., Meinschein, W. G. 1976. Seed Oil Fatty Acids: Evolutionary Significance in the Nyssaceae and Cornaceae. Biochem. Syst. Ecol., 4: 193-199.
URSOLIC-ACID
Zorina, A. D., Matyukhina, L. G., Ryabinin, A. A. 1966. Triterpenes in Some Plant Species. Chem Nat Comp, 2(4): 291.
KAEMPFEROL
Bate-Smith, E. C., Ferguson, I. K., Hutson, K., Jensen, S. R., Nielsen, B. J., Swain, T. 1975. Phytochemical Interrelationships in the Cornaceae. Biochem. Syst. Ecol., 3: 79.
Data by National Agricultural Library
Cornus mas (Cornaceae), cortex
The bark of Cornus mas, the flowering Cornus mas (Cornaceae), was often used to treat dogs with mange and this may be the reason for its name. Cornus mas (Cornaceae) is often substituted for Peruvian Bark and has been used for disease of the stomach and bowels caused by weakness. A tincture of Cornus mas (Cornaceae) Bark is believed to restore tone to the stomach in alcoholism, as well as treat dysentery and diarrhea. Traditionally, it has been used for treating nerve pain, insomnia, headaches or a migraine, anxiety, fear and nervous tension. It is used externally more than internally for the relief of muscle pain, as an anti-inflammatory and antispasmodic. The herbal extract of the bark has been used in herbal medicine for malaria (substitute for quinine), fever, pneumonia, colds and similar complaints.
The bark of the Cornus mas (Cornaceae) contains tannins, compounds which are capable of forming insoluble complexes with proteins. The fruits contain vitamin C, with astringent qualities and many different minerals. The herb is often used as a substitute for quinine and was widely used for many years to treat dysentery, in cases of malaria and chronic diarrhea. It starts moving circulation of healthy blood to the worn out matter, revitalizing it and decreasing the pain from the diseased parts. It has also been found to be useful as a remedy for colic and for bringing relaxation to the sick. Cornus mas (Cornaceae) bark can also be used to treat externally for hemorrhoids when applied to the affected areas, giving relief of the burning pain. The herb has also been consumed for intestinal parasites and ringworm. Cornus mas (Cornaceae) bark can also be used to treat external hemorrhoids.
Cornus mas (Cornaceae) bark is believed to help promote sleep with its sedative and analgesic effects. These properties may be helpful for the treatment of headaches, ovary, and uterus related pain, nervous debility, violent toothaches, dysmenorrhea, and neuralgia. The tincture is sometimes used in an ointment for fever, pneumonia, cold and similar complaints. Herbalists have used Cornus mas (Cornaceae) bark extracts to relieve whooping cough, coughs, and bronchitis, and it acts as an antispasmodic in asthma. Cornus mas (Cornaceae) has been found to be helpful in bringing down high temperatures, reduces perspiration.
Oleanolic acid and ursolic acid are isomers, that are of interest to scientists because of their number biological activities. OA has been used to lower blood sugar, and listed among the herbs used for treating diabetes. These isomers may also be useful in some herb formulas as a liver-protecting and anti-inflammatory, for viral hepatitis and lower back and knee pain associated with aging.
It has been used in tinctures to as a stomachic for loss of appetite, weak stomachs, pain in the pit of the stomach with a distended abdomen, (Boericke), heartburn and indigestion. The antispasmodic properties help relieve smooth muscle spasms along the digestive tract. The diuretic properties help to tone the kidneys promoting excretions of salts and water from the kidneys.
Ingredients: Cornus mas (Cornaceae), Structured Water, 96% Alcohol.
Non-Alcohol: Cornus mas (Cornaceae), Structured Water, and Vegetable Glycerin.
All of our ingredients are Certified Organic, Kosher, or Responsibly Wildcrafted. No genetically modified organisms (GMO’s) are involved. All other products that are distributed by us meet our high-quality standards.
Instructions: Use 10-20 drops in juice or water, under the tongue or as desired. May be taken 2-4 times daily. Shake well. Store in cool, dark place. Keep out of reach of children.
Disclaimer: The information presented herein by Herbal Alchemy is intended for educational purposes only. These statements have not been evaluated by the FDA and are not intended to diagnose, cure, treat or prevent disease. Individual results may vary, and before using any supplements, it is always advisable to consult with your own healthcare provider.
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