Kalijum permanganat rastvor 1% (Kalii permanganas solutio 1%)
Kalijum permanganat rastvor 1% (Kalii permanganas solutio) 01/2005:0121
Potassium Permanganate
Scheme Ph. Eur.
ATC (Anatomical Therapeutic Chemical Classification)
D08AX06,V03AB18
CAS registry number (Chemical Abstracts Service)
0007722-64-7
Chemical Formula K-Mn-O4
Molecular Weight 158
Therapeutic Categories
Antidote
Astringent agent
Antiseptic agent, topical
Chemical Names
Permanganic acid, potaβium salt (USP)
Potaβium permanganate (USP)
Foreign Names
Kalii permanganas (Latin)
Kaliumpermanganat (German)
Potassium permanganate de (French)
Permanganato potásico (Spanish)
Generic Names
Potassium Permanganate (OS: JAN)
Condy’s crystals (IS)
Kalii permanganas (PH: Ph. Eur. 8)
Potassium Permanganate (PH: BP 2016, JP XVI, USP 38)
Potassium permanganate (PH: Ph. Eur. 8)
Brand Names
Kalii permanganas
Kalio permanganata
Kalium hypermanganicum
PubChem POTASSIUM PERMANGANATE
Kalijum permanganat („hipermangan“, KMnO4)
U pitanju je jedan od najjačih oksidacionih agenasa. Dolazi u obliku sitnih igličastih kristalića crno-ljubičaste boje. Lako se rastvara u vodi koju boji intenzivno crveno-ljubičastom (pink) bojom. Koristi se u obliku kristalića kao dezinficijens.
U apotekama dolazi u kutijicama po 5 grama, a pre upotrebe treba napraviti rastvor terapijske koncentracije do 1%. Rastvor koncentracije 1% je roze boje. On ne sme biti jači od 1% jer je kalijum permanganat jako oksidaciono sredstvo i može oštetiti kožu. Kalijum permanganat deluje samo površinski (redukuju ga proteini kože). Primenjuje se kao dezinficijens.
Slabiji je dezinficijens od vodonik peroksida, ali deluje duže. Neprijatna nuspojava je ta što na koži ostavlja vrlo tvrdokorne smeđe mrlje mangan dioksida koje se vremenom povlače.
POTASSIUM PERMANGANATE
Potassium permanganate is a skin disinfectant and cleansing agent. It is used for soothing eczema
(skin rash) and drying wet wounds.
Dissolve a few crystals in a container of water. Dilute it to a light purple color solution like this:
Then use this solution as follows:
• Bath
Fill a tubful with the solution and use for bathing.
• Compress
Moisten strips of cotton or gauze in the solution. Wrap the strips around the affected areas.
Keep the strips in place for 10 minutes. If they dry out, add more solution.
• Soak
Fill a bathtub or a basin with enough solution to immerse the affected areas. Soak for about 10
minutes.
• Wash
Dip cotton or a gauze in the solution and use to wash affected areas.
Points To Note
• Do not make solution too concentrated or use crystals directly on affected areas as these will
irritate and burn the skin.
• Dab dry after use. It is not necessary to rinse off with clean water.
• Use either warm or cool water to make the solution.
• Potassium permanganate may stain the skin, nails and light clothing a brown colour.
• To remove fresh stains from the skin, rub over with a damp tablet of vitamin C
When in doubt, consult your doctor or pharmacist
National Skin Centre
1 Mandalay Road, Singapore 308205. Tel: 63508454
Printed: July 2012
PACKAGE LEAFLET: INFORMATION FOR THE USER
POTASSIUM PERMANGANATE 1%
solution Kalii permanganas 1%
Read all of this leaflet carefully because it contains important information for you.
This medicine is available without prescription. Nevertheless you still need to use this preparation carefully to get best results from it.
– Keep this leaflet. You may need to read it again.
– Ask your pharmacist if you need more information or advice.
– You must see a doctor if your symptoms worsen or do not improve after 7 days.
– If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
In this leaflet:
- What Potassium permanganate 1% is and what it is used for
- Before you use Potassium permanganate 1%
- How to use Potassium permanganate 1%
- Possible side effects
- How to store Potassium permanganate 1%
- Further information
- WHAT IS POTASSIUM PERMANGANATE 1% AND WHAT IT IS USED FOR
Potassium permanganate causes antiseptic effect. Potassium permanganate is a strong oxidator. In the environment, containing easy to oxidize substances (organic substances, purulence), it easily resolves into oxygen and manganese oxide, which, subject to solution concentration, either constringes, irritates, or burns the tissues. The released free oxygen atom causes the anti-microbial effect and eliminates unpleasant odor.
Just prepared potassium permanganate solution shall be used. It serves for cleaning of wounds and festers as well as cleansing of skin in case of certain diseases (e.g. eczema), especially in the event of the secondary infection.
- BEFORE YOU USE POTASSIUM PERMANGANATE 1%
Do not use Potassium permanganate 1%:
– If you are hypersensitive (allergic) to potassium permanganate.
Take special care with Potassium permanganate 1%:
– There is the risk of explosion when potassium permanganate reacts with easily oxidizing substances.
– This substance (or its concentrated solution), when exposed to skin or mucous membrane, may cause burn.
– The medicinal preparation solution dyes the, skin, nails, clothes and other fabric in brown colour.
Before using solution, please ensure that all crystals are dissolved, because if crystals get on skin, it may cause tissue damage. Do not allow potassium permanganate crystal contact with skin, mucous membrane and eyes.
Taking other medicines
Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed. As the medicament is a strong oxidator, it shall not be used concomitantly with any other topical products.
Pregnancy and breast-feeding
Ask your doctor or pharmacist for advice before taking any medicine. No harmful effects of externally used potassium permanganate have been observed for foetus and for nursed baby.
Driving and using machines
Potassium permanganate, when used externally, does not get into the circulatory system, therefore it does not affect the ability to drive and use machines.
- HOW TO USE POTASSIUM PERMANGANATE 1%
Always use Potassium permanganate 1% exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Cutaneous use.
For the treatment 0.01 % solution, which shall be prepared just before the application, is used. The solution may be used several times a day. 0.01 % solution is used to bathe a wound as well as to rinse a mouth and throat.
To prepare 0,01 % solution, put 1 mL of POTASSIUM PERMANGANATE 1% into 99 ml of warm boiled water in a glass and stir till all the KP dissolve. The solution must be lightly pink colour. If you have the impression that the effect of Potassium permanganate 1% is too strong or too weak, talk to your doctor or pharmacist.
If you use more Potassium permanganate 1% than you should When used locally, the systemic effect does mot manifest. Overuse or use of too high concentration of solution may cause irritation, inflammation, and even burn of skin or mucous membrane. Ingestion of potassium permanganate crystals or its concentrated solution may cause nausea, vomiting, liver and kidney lesion, esophagus burn, edema, bleeding from the digestive tract, disorders of the activity of the cardiovascular system, as well as may turn the oral mucous membrane brown. In such case, it is recommended to drink plenty of water, colloidal solution, as well as adsorbing materials, and, by necessity, undertake the symptomatic and sustaining treatment.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
- POSSIBLE SIDE EFFECTS
Like all medicines, Potassium permanganate 1% can cause side effects, although not everybody gets them. Sometimes the local skin or mucous membrane irritation, redness, and tingle may be experienced (especially when the mucous membrane is exposed to higher concentration of potassium permanganate solution). Potassium permanganate or its concentrated solution may dye in brown colour, irritate and burn the skin as well as mucous membrane. If potassium permanganate or potassium permanganate solution of too high concentration gets into vagina, it may cause inflammation of the mucous membrane. If you notice any side effects not mentioned or any of the side effects gets serious in this leaflet, please inform your doctor or pharmacist.
- HOW TO STORE POTASSIUM PERMANGANATE 1%
Keep out of the reach and sight of children.
Keep the bottle tightly closed in order to protect from light and moisture.
Do not use after the expiry date stated on the label. The expiry date refers to the last day of that month. 3 Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
- FURTHER INFORMATION
What Potassium permanganate 1% contains
The active substance is 0,5 g or 1,0 g of potassium permanganate (pac 50 mL or 100 mL).
What Potassium permanganate 1% looks like
Potassium permanganate 1% solution is a dark purple or brownish-black, usually having a metallic luster, crystals or powder. Potassium permanganate 1% solution is marketed in 5 g or 10 g glass vials; put in outer carton with information leaflet. Not all pack sizes may be marketed.
Marketing Authorization Holder
Manufacturer: „Biljna Alhemuja“ Branka Radičevića. 10, RS-37000 Kruševac, Srbija
This leaflet was last revised on: September 2016.