Preparati

BILJNI PREPARATI BELOG/ CRNOG DUDA:

TINKTURA – BELI/ CRNI DUD HSS I

MATIČNA TINKTURA, HIDROETANOLNI TEČNI EKSTRAKT – BELI/ CRNI DUD TM

Morus alba/ nigra tinctura

Morus folium recentis extractum ethanolicum liquidum

Morus fructus recentis extractum ethanolicum liquidum

ATC:

MeSH klasifikacija:

U skladu sa:

Eu. Ph. 8 xx.xx. 20xx.  monografijom: xxxx Morus fructus, xxxx Morus folium,

EMEA.: Assessment report on Morus alba/ nigra, folium

Fr. Ph. ANSM Morus alba/ nigra ad praeparationes homoeopathicas

(POUR PRÉPARATIONS HOMÉOPATHIQUES)

Biljni preparati u tečnom obliku (nerazblaženi ili razblaženi) za oralnu i lokalnu upotrebu.

a) Morus alba/ nigra L., folium (Mulberry fresh leaf at flowering),

b) Morus alba/ nigra L., fructus (Mulberry fresh berry).

Sastav:

a) tečni ekstrat (DER 1:1), ekstrakcioni rastvarač etanol 51% (v/v).

Morus alba nigra L., sadrži xxx (*197) hemijskih jedinjenja koja ispoljavaju xxx *(684) istraženih dejstava (*podaci ažurirani juna 2016.).

Sadržaj:

a) list minimalno 0,01% m/m rutina https://pubchem.ncbi.nlm.nih.gov/compound/5280805

b) plod minimalno 0,002% m/m kalijuma.

c) u većoj koncentraciji sadrži WATER Fruit, CARBOHYDRATES Fruit, CARBOHYDRATES Leaf, FAT Seed, PROTEIN Leaf, SOLUBLE-SUGARS Leaf, PROTEIN Seed, ASH Leaf, FIBER Leaf, PROTEIN Fruit, CELLULOSE Leaf, FAT Leaf, ASH Fruit, FIBER Fruit, RUTIN Leaf, POTASSIUM(K2O) Leaf, FAT Fruit, CALCIUM Leaf, SILICA(SIO2) Leaf, CALCIUM(CAO) Leaf, ALUMINUM(AL2O3) Leaf, PHOSPHORUS(P2O3) Leaf, POTASSIUM Fruit, MAGNESIUM(MGO) Leaf, CALCIUM Fruit, SULFUR Leaf, PHOSPHORUS Leaf, PHOSPHORUS Fruit, ASCORBIC-ACID Leaf, IRON-OXIDE(FE2O3) Leaf, PHYTATE-PHOSPHORUS Leaf, SODIUM Fruit, BETA-SITOSTEROL Leaf, BETULINIC-ACID Bark, ASCORBIC-ACID Fruit, IRON Fruit, NIACIN Fruit, RIBOFLAVIN Fruit, INOKOSTERONE Leaf, BETA-CAROTENE Fruit,  THIAMIN Fruit, BETA-ECDYSTERONE Leaf, PIPECOLIC-ACID Leaf,

d) više od svih biljaka sadrži kalijuma kao K2O

e) plod sadrži vode do 87,5%.

Indikacije:

Biljni preparati su namenjeni poboljšanju opšteg stanja organizma kroz razna naučno dokazana dejstva.

Upotreba kod      tegoba.

Dr. Džems Djuk (Dr. James Duke) u Handbook of Medicinal Herbs, 2nd Ed. (2002). CRC Press, navodi sledeće:

– ima jako dejstvo kod:

– delotvoran kod:

– u narodnoj medicini kod:

– spoljašnja primena kod:

– upotrebljava se kao:

Ca-preventiv, antioksidant, antibakterk, antiseptik, antiinflamatik, hipotenziv, antimutagenik, antitumorik, fungicid, zatim antispazmodik, antivirotik, hipoholesterolemik, hepatoprotektor, analgetik, antiulcerik, antiedemik, aldose-reductase-inhibitor, antidiabetik,

Monografija nemačke E komisije (Commission E Monographs), terapijski vodič za biljne lekove, preporučuje Morus alba fructus za slabu  , Morus alba folium  .

Doziranje i način primene:

2 mL (80 kapi) podeljeno u 2 do 4 doze.

Biljni preparat BELI DUD HSS i TM:

pojedinačna doza: 0,5-1 mL, preporučena dnevna doza (PDD): 2 mL.

Oralna (sat vremena pre obroka) i lokalna primena.

Upotreba na koži: aplicirati na obolelo mesto u tankom sloju ili obliku impregniranog zavoja.

Napraviti pauzu posle 4 nedelje neprekidne upotrebe.

Po preporukama, preparat postiže najbolje efekte pri upotrebi od 8 do 12 nedelja, duža upotreba je bezbedna uz pauze.

Kontraindikacije:

preosetljivost na aktivne supstance,

preosetljivost na biljke porodice (genus Morus, family Moraceae).

Čuvanje:

na tamnom, suvom i hladnom mestu do 20˚C, van domašaja dece i izlaganja EM zračenju,  u dobro zatvorenoj originalnoj ambalaži.

Rok upotrebe:

5 godina, posle prvog otvaranja 6 meseci.

Pakovanje:

50 mL i 100 mL, farmaceutske braon bočice standarno, 250 mL, 500 mL, 1L i 5 L na zahtev.

Nutritivne informacije:

BELI DUD HSS i TM:

a) energetska vrednost u 100 mL: 1172 kJ/ 280kcal,

u preporučenoj dnevnoj dozi (PDD) 2 mL: 23,45kJ/ 5,6kcal;

suve materije (DR) više od 1,5% (Fr. Ph.).

Bez konzervanasa, proteina, masti i ugljenih hidrata.

BELI DUD HSS i TM su rukom rađeni proizvodi. 

CENOVNIK

HSS RSD 500/ 50 mL, 1000/ 100 mL – TINKTURA,

TM  RSD 600/ 50 mL, 1200/ 100 mL – MATIČNA TINKTURA, HIDROETANOLNI TEČNI EKSTRAKT SVEŽE BILJKE.

Morus alba (Moraceae) 

Common names: White Mulberry; Sang-Pai-Pi How used: Food

Activities: 684 Chemicals w/Activities: 113 All Chemicals: 197

# Chemicals Activity

pesticide, Cancer-preventive, antioxidant, antibacterial, antiseptic, antiinflammatory, hypotensive, antimutagenic, antitumor, fungicide,

antispasmodic, antiviral, hypocholesterolemic, hepatoprotective, analgesic, antiulcer, antiedemic, aldose-reductase-inhibitor, antidiabetic, flavor,

diuretic, vasodilator, insectifuge, antiradicular, irritant, allergenic, perfumery, antifeedant, hypoglycemic, antiarthritic, antiherpetic, immunostimulant, antileukemic, antihistaminic, allelochemic, anticancer, antihypertensive, antihepatotoxic, anticataract, cardioprotective, antinociceptive, CNS-depressant, choleretic, antiaggregant, antiatherosclerotic, Lipoxygenase-Inhibitor, cytotoxic, apoptotic, antitumor-promoter, antieczemic, antidepressant, antiosteoporotic, anxiolytic, antiprostaglandin, juvabional, sedative, hemostat, antiproliferant, antiHIV, Topoisomerase-II-Inhibitor, COX-2-Inhibitor, ACE-Inhibitor, Immunomodulator, antidermatitic, antiHIV, juvabional, sedative, hemostat, antiproliferant, Topoisomerase-II-Inhibitor, chemopreventive, antifatigue, antiepileptic, antiobesity, antiPMS, antistaphylococcic, antiseborrheic, antiacne, antiasthmatic, 5-Alpha-Reductase-Inhibitor, antiseborrheic, antirheumatic, antiplaque, antiasthmatic, 5-Alpha-Reductase-Inhibitor, antiacne, Candidicide, anesthetic, Cyclooxygenase-Inhibitor, Xanthine-Oxidase-Inhibitor, antilithic, antiarrhythmic, antistress, antianemic, antimigraine, antihangover, antiLyme, laxative, myorelaxant, mutagenic, … ukupno 684 dejstava

Tinktura crnog duda (Morus nigra) 1:5 – Florida herbal pharmacy

http://www.floridaherbalpharmacy.com/monokomponentne-tinkture/tinktura-belog-duda-morus-alba

Antioxidant Activity of Mulberry Fruit Extracts

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292034/

X X X X X

Extraction and antioxidant activity of flavonoids of Morus nigra

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729996/

X X X X X

Carbohydrate polymers 2016-08-01

Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.).

Ji Won Choi, Andriy Synytsya, Peter Capek, Roman Bleha, Radek Pohl, Yong Il Park
PMID 27112865

Abstract

A water-soluble polysaccharide JS-MP-1 was isolated from Korean mulberry fruits Oddi (Morus alba L.). Sugar linkage analysis and NMR data confirmed that it is a rhamnogalacturonan type I (RG I) polymer carrying arabinan and arabinogalactan (AG II) side chains. JS-MP-1 reduced dose-dependently the viability of 3T3-L1 pre-adipocyte cells, significantly stimulated the cleavage of caspases 9 and 3 and poly (ADP-ribose) polymerase (PARP) and decreased the ratio of Bcl-2 to Bax expression level that led to mitochondrial dysfunction and apoptosis in pre-adipocyte cells. The apoptotic death was mediated by stimulation of MAPKs (ERK and p38) signalling pathway. These results suggest that JS-MP-1 is able to reduce the number of fat cells and the mass of adipose tissue via inhibition of pre-adipocyte proliferation and thus JS-MP-1 itself or a crude aqueous Oddi extract containing this polysaccharide can be used as functional ingredient of health-beneficial food supplements for the treatment or prevention of obesity disorders. Copyright © 2016 Elsevier Ltd. All rights reserved.

Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.).

http://www.sigmaaldrich.com/catalog/papers/27112865

Izvor: www.sigmaaldrich.com

German Commission E Monographs fructus

German Commission E Monographs folium

The highest total phenolic and flavonoid contents were observed in black mulberry (1422 mg gallic acid equivalents/100 g fresh matter and 276 mg quercetin equivalents/100 g fresh matter). M. alba had the highest total fat content (1.10%), followed by M. nigra (0.95%) and M. rubra (0.85%), respectively. The major fatty acids in mulberry fruits were linoleic acid (54.2%), palmitic acid (19.8%) and oleic acid (8.41%), respectively. The total soluble solids content of mulberry species varied between 15.9% (M. rubra L.) and 20.4% (M. alba L.), acidity between 0.25% (M. alba L.) and 1.40% (M. nigra L.), pH between 3.52 (M. nigra L.) and 5.60 (M. alba L.), ascorbic acid 19.4 mg/100 g (M. rubra L.) and 22.4 mg/100 g (M. alba L.), respectively.
Mineral compositions of the mulberry species were 0.83% N, 235 mg/100 g P, 1141 mg/100 g K, 139 mg/100 g Ca, 109 mg/100 g Mg, 60 mg/100 g Na, 4.3 mg/100 g Fe, 0.4 mg/100 g Cu, 4.0 mg/100 g Mn and 3.1 mg/100 g Zn, respectively.